BIO-INFORMATICS IT-723 SYLLABUS

META TAGS:- RGPV IT 7TH SEM SYLLABUS I IT BIOINFORMATICS SYLLABUS I RGPV IT 7TH SEM BIO-INFORMATICS SYLLABUS I RGPV IT-723 SYLLABUS I RGTU IT 7TH SEMESTER BIO-INFORMATICS SYLLABUS I RGPV IT-723 BIO-INFORMATICS SYLLABUS I RGPV IT 7TH SEMESTER ELECTIVE SUBJECT SYLLABUS I RGPV IT 7TH SEM ELECTIVE-2 SUBJECT LIST I RGPV IT 7TH SEM ELECTIVE SUBJECT LIST

 RGPV / RGTU BIO-INFORMATICS IT-723 SYLLABUS

Branch : Information Technology, VII Semester
Course: Bioinformatics

UNIT I:

Introduction to bioinformatics:Definition and History of Bioinformatics, Application and research of bioinformatics, finding Bioinformatics data online Bioinformatics, private and future data sources,Meta data Summary and reference systems.

UNIT II

Bioinformatics Database:Characteristics and categories of Bioinformatics database, Navigating databases, Information retrieval Systems, Sequence database Nucleotide(primary and Secondary), Protein sequence, Structure Databases: File Formats, Protein Structure, PDB, MMDB, CATH, Other Database Enzyme, MEROPS, BRENDA, Pathway database 

UNIT III

Bioinformatics Tools:Need for tools,Industry Trends,Data Mining Tools,Data Submission tools :Nucleotide Sequence, protein Submission tools,Data Analysis tools:Nucleotide Sequence, protein Sequence, Prediction Tools: Phylogenetic trees, Gene prediction, Protein Structure and Function prediction,Modeling Tools: 2D and 3D Protein Modeling.

UNIT IV

Bioinformatics Algorithms:Classification of Algorithms,Biological Algorithm,Sequence Comparison Algorithm, Substitution Matrices Algorithms, Sequence Alignment Algorithm ,Gene Prediction Algorithm.

UNIT V

Bioinformatics Software: Local Alignment Search Tool (BLAST),Purpose of BLAST,BLAST Analysis,Purpose of BLAST II,Scoring Metrics,PAM, BLOSUM, Working of BLAST. Introduction of HMMER, Practical example of HMMER.

REFERENCE BOOK:-

• Orpita Bosu and Simminder Kaur Thukral, ”Bioinformatics Databases,Tools and Algorithms”,Oxford University Press 2007.

• Harshawardhan P.bal, “Bioinformatics Principle and Applications”, TMH.

• Lesk, A.M.2002, “Introduction to Bioinformatics”, Oxford University Press.

• Rastogi, S.C. ,Mendiratta N, “Bioinformatics Concepts,Skill & Applications”, CBS Publishers.

• Claverie, J.M and Notredame C, “Bioinformatics for Dummies”, Wiley Editior.